The underlying mechanism of ototoxicity may be impairment of ion transport in the stria vascularis.
2.
The main component of this unique extracellular fluid is potassium, which is secreted from the stria vascularis.
3.
The lateral wall of the cochlear duct is formed by the spiral ligament and the stria vascularis, which produces the endolymph.
4.
The cochlear duct is bounded on three sides by the basilar membrane, the stria vascularis, and Reissner's membrane.
5.
Instead the absence of melanocytes in the stria vascularis of the inner ear results in cochlear impairment, though why this is, is not fully understood.
6.
As the basilar membrane vibrates, the hair cells attached to this membrane are rhythmically pushed up against the ATP from the stria vascularis as an energy source.
7.
The suppression of pigment cells ( melanocytes ) in the iris and in the stria vascularis of the cochlea ( inner ear ) leads to blue eyes and deafness.
8.
Dark cells are morphologically and functionally similar to marginal cells of the stria vascularis as they both display characteristics of fluid transport tissue; however, studies indicate an earlier histological and immunohistological maturity in the dark-cell areas compared to the stria vascularis.
9.
Dark cells are morphologically and functionally similar to marginal cells of the stria vascularis as they both display characteristics of fluid transport tissue; however, studies indicate an earlier histological and immunohistological maturity in the dark-cell areas compared to the stria vascularis.
10.
Stria vascularis is a rich bed of capillaries and secretory cells; Reissner's membrane is a thin membrane that separates endolymph from perilymph; and the basilar membrane is a mechanically somewhat stiff membrane, supporting the receptor organ for hearing, the organ of Corti, and determines the mechanical wave propagation properties of the cochlear system.
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